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Xiumei Zhang Selected Research

CXC 195

3/2015Tetramethylpyrazine analogue CXC195 ameliorates cerebral ischemia-reperfusion injury by regulating endothelial nitric oxide synthase phosphorylation via PI3K/Akt signaling.
1/2013Tetramethylpyrazine analogue CXC195 protects against cerebral ischemia/reperfusion injury in the rat by an antioxidant action via inhibition of NADPH oxidase and iNOS expression.

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Xiumei Zhang Research Topics

Disease

22Neoplasms (Cancer)
01/2022 - 11/2007
15Inflammation (Inflammations)
02/2021 - 07/2006
11Reperfusion Injury
07/2021 - 09/2005
11Brain Ischemia (Cerebral Ischemia)
03/2015 - 09/2005
8Infections
03/2022 - 10/2005
7Infarction (Infarctions)
03/2015 - 09/2005
6Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
03/2015 - 06/2011
5Breast Neoplasms (Breast Cancer)
08/2021 - 01/2015
5Stroke (Strokes)
01/2019 - 12/2013
5Hepatocellular Carcinoma (Hepatoma)
10/2017 - 03/2006
5Lung Neoplasms (Lung Cancer)
10/2015 - 12/2010
4Hypoxia (Hypoxemia)
12/2021 - 09/2018
4Parkinson Disease (Parkinson's Disease)
08/2018 - 04/2014
3Wounds and Injuries (Trauma)
01/2022 - 07/2009
3Carcinoma (Carcinomatosis)
01/2022 - 10/2010
3Fatigue
01/2019 - 09/2006
3Diabetic Nephropathies (Diabetic Nephropathy)
01/2019 - 12/2008
3Neuroinflammatory Diseases
09/2018 - 04/2012
3Ischemic Stroke
04/2015 - 12/2013
3Brain Injuries (Brain Injury)
01/2014 - 09/2005
2Asthma (Bronchial Asthma)
02/2021 - 01/2004
2Pain (Aches)
01/2019 - 04/2011
2Memory Disorders (Memory Loss)
01/2016 - 04/2012
2Sepsis (Septicemia)
06/2015 - 03/2013
2Necrosis
01/2015 - 12/2013
2Ischemia
01/2013 - 09/2010
2Hypertrophy
07/2010 - 12/2008
2Edema (Dropsy)
09/2009 - 07/2009
1Gastroesophageal Reflux (GERD)
04/2022
1Stomach Neoplasms (Stomach Cancer)
01/2022
1Neoplasm Metastasis (Metastasis)
01/2022
1Hyperplasia
02/2021
1Respiratory Hypersensitivity
02/2021
1Adenocarcinoma
01/2020

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
01/2020 - 09/2006
8AntioxidantsIBA
07/2021 - 09/2005
7Reactive Oxygen Species (Oxygen Radicals)IBA
07/2021 - 01/2009
7Glucose (Dextrose)FDA LinkGeneric
09/2018 - 09/2006
6Oxygen (Dioxygen)IBA
12/2021 - 12/2013
5Messenger RNA (mRNA)IBA
12/2021 - 12/2008
5EnzymesIBA
12/2021 - 12/2008
5Neuroprotective AgentsIBA
04/2016 - 09/2010
4NADPH Oxidases (NAD(P)H oxidase)IBA
01/2015 - 01/2009
3Sulfides (Thioethers)IBA
12/2021 - 08/2019
3Glutathione (Reduced Glutathione)IBA
07/2021 - 01/2015
3Estrogen ReceptorsIBA
10/2020 - 06/2006
3Biomarkers (Surrogate Marker)IBA
04/2020 - 06/2010
3Pharmaceutical PreparationsIBA
01/2019 - 01/2014
3CytokinesIBA
09/2018 - 02/2010
3Oxidopamine (6 Hydroxydopamine)IBA
08/2018 - 04/2016
3Toll-Like Receptor 9IBA
06/2015 - 02/2010
3MicroRNAs (MicroRNA)IBA
01/2015 - 05/2012
3SolutionsIBA
01/2014 - 09/2005
3hydroxysafflor yellow AIBA
11/2013 - 09/2005
3Streptozocin (Streptozotocin)FDA Link
04/2012 - 07/2006
2NADP (NADPH)IBA
03/2022 - 01/2017
2HydrogelsIBA
01/2022 - 06/2021
2Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022 - 11/2019
2Transcription Factors (Transcription Factor)IBA
01/2021 - 04/2015
2TamoxifenFDA LinkGeneric
10/2020 - 01/2019
2RNA (Ribonucleic Acid)IBA
08/2019 - 01/2016
2AlbuminsIBA
01/2019 - 09/2009
2TNF Receptor-Associated Factor 6 (TRAF6)IBA
01/2019 - 01/2018
2LipidsIBA
01/2017 - 01/2013
2Therapeutic UsesIBA
04/2016 - 01/2014
2Small Interfering RNA (siRNA)IBA
01/2016 - 01/2015
2PolymersIBA
10/2015 - 10/2014
2SilverIBA
10/2015 - 10/2014
2Ag-SP-DNCIBA
10/2015 - 10/2014
2CXC 195IBA
03/2015 - 01/2013
2tetramethylpyrazineIBA
03/2015 - 01/2013
2Advanced Glycation End ProductsIBA
10/2014 - 04/2012
2AngiotensinsIBA
01/2014 - 10/2012
2ThrombinFDA Link
11/2013 - 07/2010
2oridoninIBA
10/2011 - 10/2010
2Morphine (MS Contin)FDA LinkGeneric
04/2011 - 02/2010
2EscinIBA
09/2010 - 07/2009
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
12/2008 - 07/2006
2Cilostazol (Pletal)FDA LinkGeneric
12/2008 - 07/2006
2Matrix Metalloproteinases (MMPs)IBA
09/2008 - 11/2007
1Pepsin A (Pepsin)IBA
04/2022
1AcidsIBA
04/2022
1sulfur dioxygenaseIBA
12/2021
1alternative oxidaseIBA
12/2021
1sulfide quinone reductaseIBA
12/2021
1Carrier Proteins (Binding Protein)IBA
08/2021
1CaspasesIBA
07/2021
1Lipid PeroxidesIBA
07/2021
1Edetic Acid (EDTA)FDA Link
06/2021
1Methacholine Chloride (Methacholine)FDA Link
02/2021
1TropomyosinIBA
02/2021
1AluminumIBA
02/2021
1CollagenIBA
02/2021
1Basic-Leucine Zipper Transcription FactorsIBA
01/2021
1CCAAT-Enhancer-Binding ProteinsIBA
01/2021
1Selective Estrogen Receptor Modulators (SERM)IBA
10/2020
1Cyclin-Dependent Kinases (cdk Proteins)IBA
04/2020
1babao danIBA
01/2020
1ParaffinIBA
01/2020

Therapy/Procedure

5Therapeutics
02/2021 - 09/2010